Evidence Based Practice (EBP): "the integration of the best research evidence with clinical expertise and patient values."
(Sackett, David L., et al., Evidence-based medicine: how to practice and teach EBM. New York: Churchill Livingstone, 2000. p. 1)
Source: Sackett DL, Straus SE, Richardson WS, et al. Evidence-based medicine: how to practice and teach EBM.
PICO is a framework for defining clinical or health-related questions to be answered. In other words, PICO helps you develop search terms for research on complex medical topics:
P - Patient, Population or Problem - Who are the patients? What is the health concern?
I - Intervention or Indicator - What type of intervention are you considering?
C - Comparison or Control - Is there a comparison to be measured against?
O - Outcome(s) - What do you hope to measure, improve or affect?